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What does CELGOSIVIR stand for? 

What does CELGOSIVIR mean? This page is about the various possible meanings of the acronym, abbreviation, shorthand or slang term: CELGOSIVIR.

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CELEBRATE, CELEC, CELEP, CELF, CELG, CELGUA, CELH, CELI, CELIA, CELIAS

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What does CELGOSIVIR mean?

Celgosivir
Celgosivir, in development by Migenix for the treatment of hepatitis C virus (HCV) infection, is an oral prodrug of the natural product castanospermine that inhibits alpha-glucosidase I, an enzyme that plays a critical role in viral maturation by initiating the processing of the N-linked oligosaccharides of viral envelope glycoproteins. Celgosivir is well absorbed in vitro and in vivo, and is rapidly converted to castanospermine. Celgosivir has a novel mechanism of action (preventing the glycosylation of viral proteins by the host), and demonstrates broad antiviral activity in vitro.

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