What does APOA-1 mean in Human Genome?
This page is about the meanings of the acronym/abbreviation/shorthand APOA-1 in the Medical field in general and in the Human Genome terminology in particular.
Apolipoprotein A-I
Apolipoprotein A-I is the major protein component of high density lipoprotein (HDL) in plasma.
Submitted by JP03 on January 27, 2012
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Definition
What does APOA-1 mean?
- Apolipoprotein A-I
- The most abundant protein component of HIGH DENSITY LIPOPROTEINS or HDL. This protein serves as an acceptor for CHOLESTEROL released from cells thus promoting efflux of cholesterol to HDL then to the LIVER for excretion from the body (reverse cholesterol transport). It also acts as a cofactor for LECITHIN CHOLESTEROL ACYLTRANSFERASE that forms CHOLESTEROL ESTERS on the HDL particles. Mutations of this gene APOA1 cause HDL deficiency, such as in FAMILIAL ALPHA LIPOPROTEIN DEFICIENCY DISEASE and in some patients with TANGIER DISEASE.
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"APOA-1." Abbreviations.com. STANDS4 LLC, 2024. Web. 23 May 2024. <https://www.abbreviations.com/term/1394434>.
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