We've got 0 definitions for U937 CELL »
What does U937 CELL stand for?
What does U937 CELL mean? This page is about the various possible meanings of the acronym, abbreviation, shorthand or slang term: U937 CELL.
We couldn't find any results for your search.
Couldn't find the right meaning of U937 CELL?
Maybe you were looking for one of these abbreviations:
U4EA, U4U, U5MR, U75, U8, UA, UA-05, UA-07, UA-09, UA-12
... or use our Power Search technology to look
for more unique definitions from across the web!
Search the web
What does U937 CELL mean?
- u937 cell
- U-937 cells are a pro-monocytic model cell line used in biomedical research. They were isolated from the histiocytic lymphoma of a 37-year-old male patient in 1974. Due to the relative uniformity of expanded cultures and lower maintenance requirements these cells have been since used as an important tool for studying phagocyte differentiation and different kinds of cell-to-cell interactions. U-937 cells mature and differentiate in response to a number of soluble stimuli, adopting the morphology and characteristics of monocytes, macrophages or dendritic cells.U-937 cells are of myeloid lineage and thus secrete a large number of cytokines and chemokines either constitutively (e.g., IL-1 and GM-CSF) or in response to soluble stimuli. TNFα and recombinant GM-CSF for example independently promote IL-10 production in U937 cells. This cell line is therefore widely used for cytokine level read-outs as a result of exposure to various chemical compounds. Namely, production of IL-1β, IL-6, IL-8, IL-10, TNF-α, iNOS, COX-2 and NF-κB is commonly measured.U-937 cells bear the t(10;11)(p13;q14) translocation causing a fusion of MLLT10 and Ap-3-like clathrin assembly protein PICALM. The HLA alleles present in U-937 cells are HLA-A*03:01, A*31:01, B*18:01, B*51:01, Cw*01:02 and Cw*07:02.
Citation
Use the citation options below to add these abbreviations to your bibliography.
Style:MLAChicagoAPA
"U937 CELL." Abbreviations.com. STANDS4 LLC, 2024. Web. 24 Sep. 2024. <https://www.abbreviations.com/U937%20CELL>.
Discuss these U937 CELL abbreviations with the community:
Report Comment
We're doing our best to make sure our content is useful, accurate and safe.
If by any chance you spot an inappropriate comment while navigating through our website please use this form to let us know, and we'll take care of it shortly.
Attachment
You need to be logged in to favorite.
Log In